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PIC-OUT PLUS

Product Packing: 170 ML

Product Composition: Sodium Picosulfate 3.33 mg + Milk of Magnesia 3.75 ml + Liquid Paraffin 1.25 ml

Product Price: MRP : 140.63

PIC-OUT PLUS

Sodium Picosulfate 3.33 mg + Milk of Magnesia 3.75 ml + Liquid Paraffin 1.25 ml | SUSP. 170 ML

PIC-OUT PLUS is an oral laxative suspension containing Sodium Picosulfate, Milk of Magnesia and Liquid Paraffin. The combination provides stimulant, osmotic and stool-softening/lubricating actions and should be used for constipation only according to the current approved product label and healthcare professional guidance.

Sodium Picosulfate is a stimulant laxative activated in the colon, Milk of Magnesia (magnesium hydroxide suspension) promotes osmotic water retention in the bowel, and Liquid Paraffin acts mainly as a lubricant and stool softener. The supplied strengths are preserved exactly, but because no per-volume serving basis was supplied, the exact amount per measured dose must be verified from the approved product label.

Composition

Each labelled dose contains:

·         Sodium Picosulfate - 3.33 mg | Milk of Magnesia - 3.75 ml

·         Liquid Paraffin - 1.25 ml

·         Suspension base / excipients - q.s. The supplied brief gives ingredient quantities but does not state the measured serving volume to which they apply; exact concentration/quantity per measured dose must be verified from the approved product label.

Dosage form: Oral Suspension

Pack size: 170 ml

Uses of PIC-OUT PLUS

PIC-OUT PLUS may be used for short-term relief of constipation where this combination is approved and clinically appropriate.

·         Sodium Picosulfate stimulates colonic motility to promote bowel evacuation

·         Milk of Magnesia draws water into the bowel and helps soften stool

·         Liquid Paraffin lubricates and softens stool to facilitate passage

·         The combination may support bowel evacuation in selected patients with constipation when used appropriately

Severe or persistent abdominal pain, vomiting, abdominal swelling, blood in stool, unexplained weight loss, fever, inability to pass stool or gas, or prolonged change in bowel habits requires medical evaluation.

How PIC-OUT PLUS Works

PIC-OUT PLUS combines three laxative mechanisms:

Sodium Picosulfate: A stimulant laxative converted by colonic bacteria to an active metabolite that stimulates colonic peristalsis and promotes bowel movement.

Milk of Magnesia: Contains magnesium hydroxide, which acts mainly as an osmotic laxative by retaining water in the intestinal lumen and softening stool.

Liquid Paraffin: Acts mainly as a lubricant and stool softener, helping stool pass more easily.

The overall response depends on the exact dose, hydration, diet, bowel function, kidney function, concurrent medicines and underlying cause of constipation.

Laxatives provide symptomatic relief but should not be used to mask persistent constipation or symptoms of intestinal obstruction or other gastrointestinal disease.

 

Dosage and Direction for Use

Use PIC-OUT PLUS according to the approved product label or healthcare professional's advice. The supplied brief lists Sodium Picosulfate 3.33 mg, Milk of Magnesia 3.75 ml and Liquid Paraffin 1.25 ml but does not state the measured serving volume containing these quantities, so no per-ml or per-5-ml dose has been inferred.

Shake the suspension well before use and measure the recommended quantity accurately with a calibrated measuring cup, spoon or oral syringe as appropriate.

Maintain appropriate fluid intake unless fluids have been medically restricted. Do not use more frequently or for longer than recommended.

Children, older adults, pregnancy, breastfeeding and patients with kidney disease, electrolyte disorders or chronic bowel problems require individualized professional guidance.

Possible Side Effects

Possible adverse effects may include:

·         Abdominal cramps, abdominal discomfort, diarrhoea or urgency

·         Nausea, bloating or altered bowel habits

·         Excessive laxative use can cause dehydration and electrolyte disturbances

·         Magnesium may accumulate in significant renal impairment, while prolonged or inappropriate Liquid Paraffin use can have additional gastrointestinal and aspiration-related concerns in susceptible patients

·         Seek medical attention for severe abdominal pain, persistent vomiting or diarrhoea, marked weakness, confusion, reduced urine output, significant dehydration, allergic reaction or other serious symptoms.

Any persistent or troublesome adverse effect should be discussed with a healthcare professional.

Precautions and Contraindications

·         Review the complete approved label before use, particularly in patients with kidney impairment, dehydration, electrolyte abnormalities, swallowing difficulty or persistent gastrointestinal symptoms.

·         Avoid use in patients with known hypersensitivity to any ingredient and do not use when intestinal obstruction, ileus, acute surgical abdomen or severe unexplained abdominal pain is suspected unless specifically medically directed.

·         Patients with significant renal impairment require caution because magnesium can accumulate and cause toxicity.

·         Prolonged or frequent stimulant-laxative use may contribute to fluid/electrolyte imbalance and should be avoided unless medically supervised.

·         Liquid Paraffin requires caution in patients with swallowing difficulty or aspiration risk and should not be used indiscriminately for prolonged periods.

·         Pregnancy, breastfeeding, infants, children and frail older adults require appropriate approved-label and professional guidance.

·         Check sweeteners, flavours, preservatives and potential allergens on the final approved label.

·         Keep out of reach of children and store according to the approved pack instructions.

·         Drug Interaction Considerations

·         Diarrhoea or altered gastrointestinal transit can affect absorption of some oral medicines. Electrolyte loss from excessive laxative use may increase risks with medicines affected by potassium or fluid balance. Magnesium-containing products can also interfere with absorption of some medicines, so current medicine-specific spacing guidance should be followed.

·         Provide the healthcare professional with a complete list of prescription medicines, OTC laxatives, antacids, vitamins, minerals and supplements before regular use.

Business Growth Opportunity with PIC-OUT PLUS

PIC-OUT PLUS offers pharmaceutical distributors and healthcare entrepreneurs an opportunity to add a Sodium Picosulfate + Milk of Magnesia + Liquid Paraffin oral suspension in a convenient 170 ml pack to their gastrointestinal-care portfolio.

Constipation-relief formulations are an established therapeutic segment. Promotion must remain consistent with the final approved composition, indications, age restrictions, permitted claims, ethical pharmaceutical practice and applicable regulations.

 

Key Business Advantages

·         Triple-action constipation-relief formulation

·         Sodium Picosulfate + Milk of Magnesia + Liquid Paraffin

·         Stimulant + osmotic + lubricating/stool-softening product concept

·         Convenient 170 ml oral suspension pack

·         Suitable addition to gastrointestinal-care portfolios subject to approved formulation and indications

·         Opportunity for ethical promotion through appropriate healthcare channels

PCD Pharma Franchise Opportunity for PIC-OUT PLUS

Ethics Medinova Private Limited offers PCD Pharma Franchise opportunities for PIC-OUT PLUS in selected territories across India, subject to availability, applicable regulations and mutually agreed business terms.

Franchise partners may benefit from the company's product portfolio, promotional support, supply coordination and business assistance.

 

Franchise Support May Include

·         Monopoly-based territory opportunities, subject to availability

·         Promotional materials and visual aids consistent with approved claims

·         Product information and marketing support

·         Reliable supply coordination

·         Access to a growing pharmaceutical product portfolio

·         Professional partner assistance

Partner with Ethics Medinova to explore PCD Pharma Franchise opportunities for PIC-OUT PLUS and other quality-focused healthcare products.

Third-Party Manufacturing Support for Sodium Picosulfate + Milk of Magnesia + Liquid Paraffin Suspension

Ethics Medinova also supports eligible businesses exploring third-party manufacturing of formulations similar to PIC-OUT PLUS under their own brand, subject to applicable drug licensing, regulatory and manufacturing requirements.

Our third-party manufacturing support may include:

·         Customized approved strengths, flavour and pack requirements, subject to regulatory feasibility

·         Private-label manufacturing opportunities

·         Customized packaging and branding support

·         Product label and pack configuration assistance

·         Manufacturing coordination through suitable licensed facilities

·         Support for documentation and applicable regulatory requirements

This service may be suitable for eligible pharmaceutical companies seeking to expand an appropriately licensed gastrointestinal oral-suspension portfolio.

Frequently Asked Questions About PIC-OUT PLUS

1. What is PIC-OUT PLUS?

PIC-OUT PLUS is a 170 ml oral suspension containing Sodium Picosulfate 3.33 mg, Milk of Magnesia 3.75 ml and Liquid Paraffin 1.25 ml according to the supplied product brief.

2. What does Sodium Picosulfate do?

Sodium Picosulfate is a stimulant laxative that acts in the colon to promote bowel movement.

3. What is the role of Milk of Magnesia?

Milk of Magnesia contains magnesium hydroxide and acts mainly as an osmotic laxative, drawing water into the bowel to help soften stool.

4. What does Liquid Paraffin do?

Liquid Paraffin acts mainly as a lubricant and stool softener, helping stool pass more easily.

5. Can PIC-OUT PLUS be used for a long time?

Regular or prolonged laxative use should not be continued without professional advice because it can cause fluid/electrolyte problems and may delay evaluation of the underlying cause of constipation.

6. How should PIC-OUT PLUS be taken?

Shake well and follow the approved label or healthcare professional's directions. The supplied ingredient quantities have no stated serving-volume basis, so the exact measured dose must be verified from the approved label.

7. Is a PCD Pharma Franchise available for PIC-OUT PLUS?

Yes. Ethics Medinova offers PCD Pharma Franchise opportunities for selected products and territories, subject to availability, applicable regulations and mutually agreed terms.

8. Can this formulation be manufactured under my own brand?

Eligible businesses interested in a similar Sodium Picosulfate + Milk of Magnesia + Liquid Paraffin suspension may explore third-party manufacturing and private-label support with Ethics Medinova, subject to applicable drug licensing and regulatory requirements.

Disclaimer

PIC-OUT PLUS product information in this document is for general professional and business information. The supplied product brief states Sodium Picosulfate 3.33 mg + Milk of Magnesia 3.75 ml + Liquid Paraffin 1.25 ml, SUSP. 170 ML, but does not state the measured serving volume to which these quantities apply. No per-ml or per-5-ml concentration has therefore been inferred. Exact composition, concentration/quantity per measured dose, approved age range, indications, dosage, contraindications, warnings, interactions, excipients and regulatory status must be verified against the current approved product label before manufacture, promotion, recommending, dispensing or use. Persistent constipation, severe abdominal symptoms or suspected obstruction require appropriate clinical assessment. Patients with significant renal impairment require particular caution with magnesium-containing laxatives. This document is not a substitute for professional medical advice.

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